Antabuse is known as a medication used to treat chronic alcoholism. It contains active substance disulfiram bis(diethylthiocarbamoyl) which blocks alcohol dehydrogenase (ADH), the enzyme involved into metabolism of ethanol. Consequently blood concentration of acetaldehyde increases and causes unpleasant feelings similar to flushing, nausea, vomiting, tachycardia, lowering arterial pressure, etc. Consummation of alcoholic beverages becomes extremely unpleasant during treatment with Antabuse.

Dosage and direction
Bring it orally a minimum of 12 hours after your drinking of alcohol. While taking Anabuse avoid drinking alcoholic beverages within a form: beer, wine, aftershave lotions, liquid medications, mouthwash, colognes. Consider the pill with a full glass of water.

Precautions
Inform your doctor if you got issues with heart, stomach or duodenal ulcers, disorders of cerebral circulation and disulfiram psychosis in history. Cautiousness is to be exercised while using Anabuse inside the patients over 60 years of age.

Contraindications
Antabuse cannot be utilized in the patients with severe diseases of those cardiovascular system, neuritis of those auditory nerve, glaucoma, optic neuritis, bronchial asthma, emphysema, pulmonary tuberculosis, severe hepatic impairment, diabetes, hyperthyroidism, mental illness, acute peptic ulcer, diseases of kidneys, malignant tumor, polyneuritis, pregnant and breastfeeding women, aversion towards the medication.

Possible negative effect
A typical unwanted effects include: restlessness, headache, drowsiness, skin rash, acne, changes in vision, garlic-like aftertaste. More rare but serious adverse reactions may occur: tingling hands or feet, fatigue, weakness, strong stomach pains, absence of appetite, nausea, vomiting, dark urine, yellowing of the eyes or skin. If you have serious side effects, they become bothersome and worsen notify your physician and seek immediate medical help.

Drug interaction
Inform your health care advisor about all medications and herbal additives you are taking and particularly about tricyclic antidepressants similar to imipramine (Tofranil), amitriptyline (Elavil), doxepin (Sinequan), nortriptyline (Pamelor), isoniazid (Nydrazid), phenytoin (Dilantin), warfarin (Coumadin), metronidazole (Flagyl), theophylline (Theo-Dur), MAO inhibitors such as phenelzine (Nardil), isocarboxazid (Marplan), or tranylcypromine (Parnate); benzodiazepine similar to diazepam (Valium), alprazolam (Xanax), clorazepate (Tranxene), temazepam (Restoril), chlordiazepoxide (Librium), triazolam (Halcion), lithium (Lithobid, Eskalith, others).

Missed dose
Never have a double dose of the medication. Whether it is almost time of the next dose just skip the missed portion and continue to move the drugs while using schedule.

Overdose
Immediate chunks of money is called for in case of Anabuse overdose which symptoms include absence of coordination, nausea, vomiting, dizziness, numbness and tingling, and seizures.

Storage
Store at room temperature of 59-86 F (15-30 C) faraway from moisture and sunlight. Avoid moisture (bathroom).